Recombinant Human Heat shock cognate 71 kDa protein/HSC70 Protein
The Recombinant Human Heat shock cognate 71 kDa protein/HSC70 Protein is a biologically active recombinant protein that plays a significant role in various cellular processes and signaling pathways in human biology. This protein is widely employed in immunological research, cell biology studies, protein-protein interaction analyses, and therapeutic development, providing researchers with a reliable tool for investigating Heat shock cognate 71 kDa protein/HSC70 function and its implications in health and disease.
This product (SKU: RPCB2200) is produced using advanced expression systems and features a N-His tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 72.4 kDa with an observed molecular weight of 60-70 kDa under denaturing conditions, achieving ≥ 90 % as determined by SDS-PAGE., ensuring exceptional quality and consistency for research applications.
Key Features
High Purity by Affinity Chromatography
Mammalian & Bacterial Expression Systems
High lot-to-lot consistency via strict QC
Product Name:
Recombinant Human Heat shock cognate 71 kDa protein/HSC70 Protein
SKU:
RPCB2200
Size:
100 μg
Reactivity:
Human
Synonyms:
Heat shock cognate 71 kDa protein, Heat shock 70 kDa protein 8, HSPA8, HSC70, HSP73, HSPA10, Lipopolysaccharide-associated protein 1, LPS-associated protein 1, LAP-1, HEL-33, NIP71
High quality, high purity and low endotoxin recombinant Recombinant Human Heat shock cognate 71 kDa protein/HSC70 Protein (RPCB2200), tested reactivity in E.coli and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:
Please contact us for more information.
Purity:
≥ 90 % as determined by SDS-PAGE.
Formulation:
Lyophilized from a 0.22 μm filtered solution of PBS, 10% glycerol, pH 7.5. Contact us for customized product form or formulation.
Reconstitution:
Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Storage:
Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
HSC70, also known as HSPA8, is a member of the heat shock protein family. It is homologous to other heat shock proteins. The heat shock protein 70 family is comprised of both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA8 belongs to the heat-shock cognate subgroup. Members of the human heat-shock protein multigene family have several highly conserved proteins with structural and functional properties in common but vary in the extent of their inducibility in response to metabolic stress. HSPA8 is constitutively expressed and performs functions related to normal cellular processes. This protein binds to nascent polypeptides to facilitate correct protein folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during the transport of membrane components through the cell.
Recombinant Human Heat shock cognate 71 kDa protein/HSC70 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
