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Human Hyaluronidase/HYAL1 Recombinant Protein (RPES0861)

SKU:
RPES0861
Product Type:
Recombinant Protein
Species:
Human
$510
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Description

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Human Hyaluronidase/HYAL1 Recombinant Protein

The gene for lysosomal hyaluronidase is HYAL1/Hyaluronidase-1. Intracellular hyaluronidases break down one of the extracellular matrix's major glycosaminoglycans, hyaluronan. Hyaluronan has been shown to help with cell proliferation, migration, and differentiation. Hyaluronidase-1, also known as HYAL1, is the major hyaluronidase in plasma and is active at an acidic pH. Mucopolysaccharidosis type IX, also known as hyaluronidase deficiency, is associated with a mutation in this gene. The gene is located in a tumour-suppressive area of chromosome 3p21.3. Natowicz Syndrome and Mucopolysaccharidosis, Type Ix are diseases linked to HYAL1. Chondroitin sulfate/dermatan sulphate metabolism and glycosaminoglycan metabolism are two related pathways of HYAL1/Hyaluronidase-1. Human Hyaluronidase/HYAL1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.