Description
Recombinant Human IL-13RA1/CD213a1 Protein
The Recombinant Human IL-13RA1/CD213a1 Protein is a biologically active recombinant protein that plays a significant role in various cellular processes and signaling pathways in human biology. This protein is widely employed in immunological research, cell biology studies, protein-protein interaction analyses, and therapeutic development, providing researchers with a reliable tool for investigating IL-13RA1/CD213a1 function and its implications in health and disease.
This product (SKU: RPCB1036) is produced using HEK293 cells and features a C-His tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 39.89 kDa with an observed molecular weight of 55-70 kDa under denaturing conditions, achieving ≥ 95 % as determined by SDS-PAGE., ensuring exceptional quality and consistency for research applications.
Key Features
| High Purity by Affinity Chromatography | |
| Mammalian & Bacterial Expression Systems | |
| High lot-to-lot consistency via strict QC | 
| Product Name: | Recombinant Human IL-13RA1/CD213a1 Protein | 
| SKU: | RPCB1036 | 
| Size: | 20 μg , 50 μg | 
| Reactivity: | Human | 
| Synonyms: | CD213A1, CT19, IL-13Ra, NR4, IL13RA1, CT19, IL-13Ra, NR4 | 
| Tag: | C-His | 
| Expression Host: | HEK293 cells | 
| Calculated MW: | 39.89 kDa | 
| Observed MW: | 55-70 kDa | 
| Gene ID: | 3597 | 
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human IL-13RA1/CD213a1 Protein (RPCB1036), tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. | 
| Endotoxin: | < 0.1 EU/μg of the protein by LAL method. | 
| Purity: | ≥ 95 % as determined by SDS-PAGE. | 
| Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. | 
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. | 
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. | 
Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. IL13RA1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. This subunit together with IL4RA can form a functional receptor for IL13. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2. IL13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
            
            