Description
Recombinant Human IL-17A&IL-17F Protein
The Recombinant Human IL-17A&IL-17F Protein is a biologically active recombinant protein that plays a significant role in various cellular processes and signaling pathways in human biology. This protein is widely employed in immunological research, cell biology studies, protein-protein interaction analyses, and therapeutic development, providing researchers with a reliable tool for investigating IL-17A&IL-17F function and its implications in health and disease.
This product (SKU: RPCB1566) is produced using HEK293 cells and features a C-His tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 15.1 kDa (IL-17A), 15.7 kDa (IL-17F) with an observed molecular weight of 16 kDa(IL-17A) , 27 kDa(IL-17F) under denaturing conditions, achieving ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 % as determined by HPLC., ensuring exceptional quality and consistency for research applications.
Key Features
High Purity by Affinity Chromatography | |
Mammalian & Bacterial Expression Systems | |
High lot-to-lot consistency via strict QC |
Product Name: | Recombinant Human IL-17A&IL-17F Protein |
SKU: | RPCB1566 |
Size: | 100 μg |
Reactivity: | Human |
Synonyms: | IL-17A, Interleukin-17A, CTLA-8, IL-17, IL-17F, IL24, ML-1, Interleukin-17F |
Tag: | C-His |
Expression Host: | HEK293 cells |
Calculated MW: | 15.1 kDa (IL-17A), 15.7 kDa (IL-17F) |
Observed MW: | 16 kDa(IL-17A) , 27 kDa(IL-17F) |
Gene ID: | 112744 |
Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human IL-17A&IL-17F Protein (RPCB1566), tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
Endotoxin: | < 1 EU/μg of the protein by LAL method. |
Purity: | ≥ 95 % as determined by Tris-Bis PAGE;≥ 95 % as determined by HPLC. |
Reconstitution: | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
Interleukin?17A (IL?17A), also known as CTLA?8, is a 15?20 kDa glycosylated cytokine that plays an important role in anti?microbial and chronic inflammation. The six IL?17 cytokines (IL?17A?F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.