Interleukin-20 Receptor Subunit ? (IL20RA) is a single-pass type I membrane protein that is a member of the type II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29 amino acid signal peptide; a 221 amino acid extracellular domain with two fibronectin type-III domains; a 24 amino acid transmembrane region; and a 279 amino acid intracellular domain. IL20RA is widely expressed with highest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB; and the complex serves as a receptor for IL19; IL20 and IL24. IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26.
Product Name:
Human IL-20RA/IL-20R1 Recombinant Protein (RPES1257)
Product Code:
RPES1257
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Interleukin-20 Receptor Subunit Alpha, IL-20 Receptor Subunit Alpha, IL-20R-Alpha, IL-20RA, Cytokine Receptor Class-II Member 8, Cytokine Receptor Family 2 Member 8, CRF2-8, IL-20R1, ZcytoR7, IL20RA
Accession:
Q9UHF4
Sequence:
Val30-Lys250
Fusion tag:
C-6His
Activity:
Immobilized Human IL-20(Cat: PKSH032630) at 2µg/ml(100 ?l/well) can bind Human IL-20RA-His. The ED50 of Human IL-20RA-His is 3.5 ug/ml .
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Interleukin-20 Receptor Subunit alpha is produced by our Mammalian expression system and the target gene encoding Val30-Lys250 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
26.3 kDa
AP Mol Mass:
40 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
