Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion; gonadal hormone secretion; germ cell development and maturation; erythroid differentiation; insulin secretion; nerve cell survival; embryonic axial development or bone growth; depending on their subunit composition. Inhibins appear to oppose the functions of activins;Inhibins and activins inhibit and activate; respectively; the secretion of follitropin by the pituitary gland.
Product Name:
Inhibin Beta C Chain/INHBC Recombinant Protein (RPES1427)
Product Code:
RPES1427
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Inhibin Beta C Chain, Activin Beta-C Chain, INHBC
Accession:
P55103
Sequence:
Gly237-Ser352
Fusion tag:
N-6His
Activity:
Immobilized Human INHBC-His at 0.8µg/ml(100 ?l/well) can bind Human ACVR2A-Fc(Cat: PKSH032039). The ED50 of Human INHBC-His is 6.73 ug/ml .
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Inhibin beta C Chain is produced by our E.coli expression system and the target gene encoding Gly237-Ser352 is expressed with a 6His tag at the N-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
14.8 kDa
AP Mol Mass:
16 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 4mM HCl; 1mM DTT.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
