Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. MAPKSP1 interacts with MAP2K1/MEK1 and MAPK2 and enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade.
Product Name:
Human LAMTOR3/MP1 Recombinant Protein (RPES4401)
Product Code:
RPES4401
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Ragulator Complex Protein LAMTOR3, Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3, MEK-Binding Partner 1, Mp1, Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1, Mitogen-Activated Protein Kinase Scaffold Protein 1, LAMTOR3, MAP2K1IP1, MAPKSP1
Accession:
Q9UHA4
Sequence:
Met 1-Val124
Fusion tag:
N-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Mitogen-Activated Protein Kinase Scaffold Protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Val124 is expressed with a 6His tag at the N-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
15.8 kDa
AP Mol Mass:
15 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 100mM NaCl, 5mM DTT, 30% Glycerol, pH 8.0.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
