Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.
Product Name:
Human MGAT2/GlcNAc-TII Recombinant Protein (RPES4280)
Product Code:
RPES4280
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Alpha-1,6-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase, Beta-1,2-N-acetylglucosaminyltransferase II, GlcNAc-T II, NT-II, Mannoside Acetylglucosaminyltransferase 2, N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase II, MGAT2
Accession:
Q10469
Sequence:
Arg30-Gln447
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Mannoside Acetylglucosaminyltransferase 2 is produced by our Mammalian expression system and the target gene encoding Arg30-Gln447 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
49.3 kDa
AP Mol Mass:
50 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM TrisHCl,150mM NaCl, pH8.0 .
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
