Description
Recombinant Human Neutrophil cytosol factor 1/NCF1 Protein
The Recombinant Human Neutrophil cytosol factor 1/NCF1 Protein is a biologically active recombinant protein that plays a significant role in various cellular processes and signaling pathways in human biology. This protein is widely employed in immunological research, cell biology studies, protein-protein interaction analyses, and therapeutic development, providing researchers with a reliable tool for investigating Neutrophil cytosol factor 1/NCF1 function and its implications in health and disease.
This product (SKU: RPCB0130) is produced using advanced expression systems and features a C-His tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 45.6 kDa with an observed molecular weight of 45-50 kDa under denaturing conditions, achieving ≥ 95 % as determined by SDS-PAGE., ensuring exceptional quality and consistency for research applications.
Key Features
| High Purity by Affinity Chromatography | |
| Mammalian & Bacterial Expression Systems | |
| High lot-to-lot consistency via strict QC |
| Product Name: | Recombinant Human Neutrophil cytosol factor 1/NCF1 Protein |
| SKU: | RPCB0130 |
| Size: | 10 μg , 50 μg |
| Reactivity: | Human |
| Synonyms: | NCF1, NOXO2, SH3PXD1A, NCF-47K, NCF-1, p47-phox, Nox organizer 2, Neutrophil cytosol factor 1, Neutrophil NADPH oxidase factor 1, 47 kDa neutrophil oxidase factor, 47 kDa autosomal chronic granulomatous disease protein |
| Tag: | C-His |
| Calculated MW: | 45.6 kDa |
| Observed MW: | 45-50 kDa |
| Gene ID: | 653361 |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human Neutrophil cytosol factor 1/NCF1 Protein (RPCB0130), tested reactivity in E.coli and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | < 1 EU/μg of the protein by LAL method. |
| Purity: | ≥ 95 % as determined by SDS-PAGE. |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, 1 mM DTT, pH 8.0. Contact us for customized product form or formulation. |
| Reconstitution: | Please contact us for reconstitution instructions. |
| Storage: | Store at -20℃. Store the lyophilized protein at -20℃ to -80℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
NCF1 is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This protein is essential for activation of the NADPH oxidase complex, which is essential for superoxide production. It cooperates with NCF2 to form a core association in the complex, interacting with NCF4, CYBB and CYBA. Mutations in the NCF1 gene have been associated with chronic granulomatous disease.
