Nesfatin-1 is a metabolic polypeptide that is produced in the N-terminal part of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the mammalian hypothalamus. It is involved in hunger and fat storage regulation. Nesfatin-1 is also found in the brain and promotes beta cell function, gastric endocrine cells, and fat cells. Nesfatin-1 inhibits food intake and energy metabolism in Leptin-independent ways. Nesfatin-1 may also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance. Human Nucleobindin-2/NUCB2 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human Nucleobindin-2/NUCB2 Recombinant Protein (RPES0707)
Product Code:
RPES0707
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Nucleobindin-2, DNA-binding protein NEFA, Gastric cancer antigen Zg4, Prepronesfatin, Nesfatin-1, NUCB2, NEFA
Accession:
P80303
Sequence:
Val25-Leu106
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Nucleobindin-2 is produced by our E.coli expression system and the target gene encoding Val25-Leu106 is expressed.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
9.6 kDa
AP Mol Mass:
10 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 10mM Sodium Phosphate,pH6.5.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
