Protein Phosphatase 1G (PP1MG) is a cytoplasmic protein that belongs to the PP2C family. PPM1G is widely expressed; it is abundant in testis; skeletal muscle; and heart. PPM1G is a negative regulator of cell stress response pathways. PPM1G is responsible for the dephosphorylation of Pre-mRNA splicing factors; an important factor for the formation of functional spliceosome. PPM1G also plays a role in regulating cell cycle progression.
Product Name:
Human PPM1G/PP2C-gamma Recombinant Protein (RPES3325)
Product Code:
RPES3325
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Protein Phosphatase 1G, Protein Phosphatase 1C, Protein Phosphatase 2C Isoform Gamma, PP2C-Gamma, Protein Phosphatase Magnesium-Dependent 1 Gamma, PPM1G, PP2CG,PP2CGAMMA
Accession:
O15355
Sequence:
Met317-Asp546
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Protein Phosphatase 1G is produced by our E.coli expression system and the target gene encoding Met317-Asp546 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
26.2 kDa
AP Mol Mass:
30 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 25mM TrisHCl; 1mM DTT; 1mM EDTA; 2mM ?-ME; 20% Glycerol; pH 7.5.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
