Description
Recombinant Human PRDX4 Protein
The Recombinant Human PRDX4 Protein is a biologically active recombinant protein that plays a significant role in various cellular processes and signaling pathways in human biology. This protein is widely employed in immunological research, cell biology studies, protein-protein interaction analyses, and therapeutic development, providing researchers with a reliable tool for investigating PRDX4 function and its implications in health and disease.
This product (SKU: RPCB1920) is produced using E.coli and features a N-His tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 28.9 KDa with an observed molecular weight of 30 KDa under denaturing conditions, achieving ≥ 95 % as determined by SDS-PAGE., ensuring exceptional quality and consistency for research applications.
Key Features
| High Purity by Affinity Chromatography | |
| Mammalian & Bacterial Expression Systems | |
| High lot-to-lot consistency via strict QC |
| Product Name: | Recombinant Human PRDX4 Protein |
| SKU: | RPCB1920 |
| Size: | 10 μg , 50 μg |
| Reactivity: | Human |
| Synonyms: | Peroxiredoxin-4, Antioxidant Enzyme AOE372, AOE37-2, Peroxiredoxin IV, Prx-IV, Thioredoxin Peroxidase AO372, Thioredoxin-Dependent Peroxide Reductase A0372, PRDX4 |
| Tag: | N-His |
| Expression Host: | E.coli |
| Calculated MW: | 28.9 KDa |
| Observed MW: | 30 KDa |
| Gene ID: | 10549 |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human PRDX4 Protein (RP03163LQ), tested reactivity in E.coli and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | < 1 EU/μg of the protein by LAL method. |
| Purity: | ≥ 95 % as determined by SDS-PAGE. |
| Formulation: | Supplied as a 0.22 μm filtered solution in PBS, pH 7.4. Contact us for customized product form or formulation. |
| Storage: | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
