PTH2, also known as PTRH2, is a mitochondrial protein which belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. When in the cytoplasm, PTRH2 regulates the function of 2 transcriptional regulators, TLE5 and TLE1, thus promoting caspase-independent cell death.
Product Name:
Human PTH2/PTRH2 Recombinant Protein (RPES3756)
Product Code:
RPES3756
Size:
100 µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
BIT1,CFAP37,CGI-147,IMNEPD,PTH,PTH 2,PTH2,PTRH2
Accession:
Q9Y3E5
Sequence:
Gly63-Tyr179
Fusion tag:
N-His
Endotoxin:
Please contact us for more information.
Protein Construction:
A DNA sequence encoding the human PTRH2 (Q9Y3E5) (Gly63-Tyr179) was expressed with a polyhistidine tag at the N-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
14.5 kDa
AP Mol Mass:
14 kDa
Formulation:
Lyophilized from sterile 20mM Tris, 10% glycerol, pH 8.0
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
