Repulsive guidance molecule A?RGMA? is a cell membrane protein and belongs to the repulsive guidance molecule (RGM) family. It interacts with NEO1; BMP2 and BMP4. RGMA is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.
Product Name:
Human RGMA Recombinant Protein (RPES2339)
Product Code:
RPES2339
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Repulsive guidance molecule A,RGM domain family member A,RGM
Accession:
NP_064596.2
Sequence:
Pro169-Gly422
Fusion tag:
N-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Repulsive guidance molecule A is produced by our E.coli expression system and the target gene encoding Pro169-Gly422 is expressed with a 6His tag at the N-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
29.8 kDa
AP Mol Mass:
30 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM Tris;150mM NaCl;pH8.0.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
