MST3 encodes a serine/threonine protein kinase that functions upstream of mitogen-activated protein kinase (MAPK) signaling. The encoded protein is cleaved into two chains by caspases; the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death. There is a pseudogene for this gene on chromosome X. Alternative splicing results in multiple transcript variants.
Product Name:
Human STK24/MST3 Recombinant Protein (RPES0815)
Product Code:
RPES0815
Size:
50 µg
Species:
Human
Expressed Host:
Baculovirus-Insect Cells
Synonyms:
HEL-S-95,MST3,MST3B,RP11-111L24.5,STE20,STK3
Accession:
Q9Y6E0-2
Sequence:
Met 1-His 431
Fusion tag:
N-His
Activity:
The specific activity was determined to be 62 nmol/min/mg using synthetic PKCtide peptide (ERMRPRKRQGSVRRRV) as substrate.
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the human STK24 isoform A (Q9Y6E0-2) (Met 1-His 431) was expressed, with a polyhistidine tag at the N-terminus.
