MST1 protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.
Product Name:
Human STK4/MST1 Recombinant Protein (RPES1285)
Product Code:
RPES1285
Size:
50 µg
Species:
Human
Expressed Host:
Baculovirus-Insect Cells
Synonyms:
KRS2,MST1,TIIAC,YSK3
Accession:
Q13043-1
Sequence:
Glu 2-Phe 487
Fusion tag:
N-His
Activity:
The specific activity was determined to be 253 nmol/min/mg using MBP as substrate.
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the human STK4 isoform 1 (Q13043-1) (Glu 2-Phe 487) was expressed, with a polyhistidine tag at the N-terminus.
