Ubiquitin/ISG15-Conjugating Enzyme E2 L6 (UBE2L6) is an enzyme member of the E2 ubiquitin-conjugating enzyme family. UBE2L6 plays a same function as UBE2D; it catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. UBE2L6 promotes ubiquitination and subsequent proteasomal degradation of FLT3. It has functions in the E6/E6-AP-induced ubiquitination of p53/TP53.
Product Name:
Human Ube2L6 Recombinant Protein (RPES1948)
Product Code:
RPES1948
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Ubiquitin/ISG15-Conjugating Enzyme E2 L6, Retinoic Acid-Induced Gene B Protein, RIG-B, UbcH8, Ubiquitin Carrier Protein L6, Ubiquitin-Protein Ligase L6, UBE2L6, UBCH8
Accession:
O14933-1
Sequence:
Met 1-Ser153
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Ubiquitin-Conjugating Enzyme E2 L6 is produced by our E.coli expression system and the target gene encoding Met1-Ser153 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
18.8 kDa
AP Mol Mass:
17 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 50mM HEPES; 100mM NaCl; pH 8.0.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
