The VILIP1/VSNL1 gene belongs to the visinin/recoverin family of calcium sensor proteins present in neurons. VILIP1/VSNL1 is highly expressed in cerebellar granule cells, where it creates calcium-dependent associations with membranes and modulates intracellular signalling pathways in the central nervous system by regulating adenylyl cyclase activity. VSNL1 has been linked to two neurological diseases: acute encephalopathy with biphasic seizures and late reduced diffusion, and alzheimer's disease. Human VSNL1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human VSNL1 Recombinant Protein (RPES2563)
Product Code:
RPES2563
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Visinin-Like Protein 1, VILIP, VLP-1, Hippocalcin-Like Protein 3, HLP3, VSNL1, VISL1
Accession:
P62760
Sequence:
Met 1-Lys191
Fusion tag:
N-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Visinin-Like Protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Lys191 is expressed with a 6His tag at the N-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
24.3 kDa
AP Mol Mass:
32 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM Tris, 20mM NaCl, pH 8.0.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
