Xaa-Pro aminopeptidase 2 (XPNPEP2) belongs to the peptidase M24B family of metalloproteases. Human XPNPEP2 is widely expressed in various tissues; such as kidney; lung; heart; placenta; liver; small intestine and colon. However; it doesnÂ’t express in brain; skeletal muscle; pancreas; spleen; thymus; prostate; testis and ovary. XPNPEP2 is a Homotrimer which binds 2 manganese ions per subunit. The metalloprotease XPNPEP2 may play a role in the inflammatory process and other reactions produced in response to injury or infection and the metabolism of the vasodilator bradykinin.
Recombinant Human Xaa-Pro Aminopeptidase 2 is produced by our Mammalian expression system and the target gene encoding His22-Ala650 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
71.6 kDa
AP Mol Mass:
78 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM TrisHCl; 150mM NaCl; pH 8.0.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
