Anterior gradient protein 3 (AGR3) is an 18 kDa member of the AGR family of proteins. It is expressed in the ciliated cells of the airway epithelium, not detected in the mucous cells. Mature human AGR3 shares 92% amino acid sequence identity with mouse AGR3. It is required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. AGR3 might be involved in the regulation of intracellular calcium in tracheal epithelial cells.
Product Name:
Mouse AGR3 Recombinant Protein (RPES2177)
Product Code:
RPES2177
Size:
10µg
Species:
Mouse
Expressed Host:
Human Cells
Synonyms:
Anterior gradient protein 3, AGR3,AG3,BCMP11
Accession:
Q8R3W7
Sequence:
Ile21-Leu165
Fusion tag:
C-His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Mouse AGR3 is produced by our Mammalian expression system and the target gene encoding Ile21-Leu165 is expressed with a 6His tag at the C-terminus.
Purity:
> 90% as determined by reducing SDS-PAGE.
Mol Mass:
18.1 kDa
AP Mol Mass:
16 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM Tris,10%Glycerol,100mM NaCl,pH8.0.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
