Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions by interacting with the chemokine receptor CXCR3. CXCL9 acts as a Th1 (type 1 helper T) cell chemoattractant and plays a role in the growth, activation and movement of cells associated with immune and inflammatory responses, and in tumour growth inhibition. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4.
Product Name:
Mouse CXCL9 Recombinant Protein (RPES1869)
Product Code:
RPES1869
Size:
10µg
Species:
Mouse
Expressed Host:
Human Cells
Synonyms:
C-X-C motif chemokine 9, Gamma-interferon-induced monokine, Monokine induced by interferon-gamma, MIG, MuMIG, Protein m119, Small-inducible cytokine B9, Cxcl9, Mig, Scyb9
Accession:
P18340
Sequence:
Thr22-Thr126
Fusion tag:
C-His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Mouse CXCL9 is produced by our Mammalian expression system and the target gene encoding Thr22-Thr126 is expressed with a 6His tag at the C-terminus.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
13 kDa
AP Mol Mass:
20-25 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
