Follistatin-like 1 (FSTL1) is a secreted glycoprotein that has been grouped into the follistatin family of proteins. FSTL1 is composed of a follistatin domain and two non-functional calcium-binding motifs. It was originally cloned as a TGFβ1 inducible factor but subsequently shown to regulate diverse developmental pathways and tissue homeostasis. Ablation of the FSTL1 gene in the mouse results in several structural developmental defects and neonatal lethality due to respiratory failure. FSTL1 suppresses BMP signaling, but the precise mechanism of its action has not been elucidated. FSTL1 is expressed in the human placenta, mainly in extravillous trophoblasts.
Product Name:
Mouse FSTL1 Recombinant Protein (RPES0810)
Product Code:
RPES0810
Size:
10µg
Species:
Mouse
Expressed Host:
Human Cells
Synonyms:
Follistatin-related protein 1, Follistatin-like protein 1, TGF-beta-inducible protein TSC-36, Fstl1
Accession:
Q62356
Sequence:
Glu19-Ile306
Fusion tag:
C-Fc
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Mouse Follistatin-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Glu19-Ile306 is expressed with a Fc tag at the C-terminus.
Purity:
> 95 % as determined by SDS-PAGE
Mol Mass:
59.6 kDa
AP Mol Mass:
70-85 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
