Description
| Product Name: | Recombinant Mouse IL-7 Protein |
| SKU: | RPCB0094 |
| Size: | 10µg |
| Tag: | C-6His |
| Reactivity: | Mouse |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Mouse IL-7 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | < 0.01EU/μg |
| Formulation: | Supplied as a 0.22 μm filtered solution in PBS, pH 7.4. |
| Gene ID: | 16196 |
IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCR?) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes.
| Storage: | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | P10168 |
 | Recombinant Mouse IL-7 Proteinwas determined by SDS-PAGE with Coomassie Blue, showing a band at 15-25 kDa. |
 | Recombinant Mouse IL-7 stimulates cell proliferation of the murine 2E8 cells. The ED₅₀ for this effect is 0.8-3.2 ng/mL, corresponding to a specific activity of 3.23×105~1.25×106 units/mg. |
