Description
Recombinant Mouse PDGFR-alpha/CD140a Protein
The Recombinant Mouse PDGFR-alpha/CD140a Protein is a high-quality recombinant protein designed for murine biological research applications. This protein serves as an essential reagent in mouse model studies, comparative immunology research, and preclinical therapeutic evaluations, enabling scientists to investigate PDGFR-alpha/CD140a biology and its relevance to human disease mechanisms through translational research approaches.
This product (SKU: RPCB0985) is produced using HEK293 cells and features a C-Fc tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 83.2 kDa with an observed molecular weight of 120-150 kDa under denaturing conditions, achieving ≥ 95 % as determined by SDS-PAGE., ensuring exceptional quality and consistency for research applications.
Key Features
| High Purity by Affinity Chromatography | |
| Mammalian & Bacterial Expression Systems | |
| High lot-to-lot consistency via strict QC |
| Product Name: | Recombinant Mouse PDGFR-alpha/CD140a Protein |
| SKU: | RPCB0985 |
| Size: | 10 μg , 50 μg |
| Reactivity: | Mouse |
| Synonyms: | Platelet-derived growth factor receptor alpha, PDGF-R-alpha, PDGFR-alpha, Alpha platelet-derivedgrowth factor receptor, CD140 antigen-like family member A, Platelet-derived growth factor alphareceptor, CD140a, PDGFRA |
| Tag: | C-Fc |
| Expression Host: | HEK293 cells |
| Calculated MW: | 83.2 kDa |
| Observed MW: | 120-150 kDa |
| Gene ID: | 18595 |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Mouse PDGFR-alpha/CD140a Protein (RPCB0985), tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | < 1 EU/μg of the protein by LAL method. |
| Purity: | ≥ 95 % as determined by SDS-PAGE. |
| Formulation: | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation. |
| Reconstitution: | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
Platelet-derived growth factor receptors (PDGFR) are cell surface tyrosine kinase receptors for members of theplatelet-derived growth factor (PDGF) family. The PDGF family consists of PDGF-A, -B, -C and -D, which formeither homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomericforms. PDGFs bind to the protein tyrosine kinase receptors PDGF receptor- α and - β. These two receptorisoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -αα,#NAMEsignaling has been linked to a number of proliferative disorders.
 | Recombinant Mouse PDGFR-alpha/CD140a Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue. |
