Alpha-N-acetylgalactosaminide alpha -2,6-sialyltransferase 2, is a type?II membrane protein localized in the Golgi network and catalyzes 2,6-sialylation of the Tn antigen. Sialyl-Tn antigen is highly expressed in several human carcinomas and is associated with carcinoma aggressiveness and poor prognosis.?it has been reported that disregulation of this gene is involved in the pathogenesis of IgA nephropathy, a common kidney disease that occurs when antibody IgA accumulates in kidneys (4). The enzyme may also be used to synthesize a cancer vaccine.
Recombinant Mouse ST6GALNAC2 is produced by our Mammalian expression system and the target gene encoding Ser28-Arg373 is expressed with a 6His tag at the C-terminus.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
40.4 kDa
AP Mol Mass:
45 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 50mMTris,150mMNaCl,pH7.5.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
