Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B) is a member of the Tumor Necrosis Factor Receptor Superfamily. TNFRSF1B contains four TNFR-Cys repeats. TNFRSF1B can be cleaved into the following 2 chains: Tumor necrosis factor receptor superfamily member 1b and membrane form and Tumor necrosis factor-binding protein 2. TNFRSF1B is a receptor with high affinity for TNFSF2/TNF-? and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-?. TNFRSF1B mediates most of the metabolic effects of TNF-?. TNF-?-induced apoptosis suggests that it regulates TNF-? function by antagonizing its biological activity.
Product Name:
Mouse TNFRSF1B/CD120b Recombinant Protein (RPES0477)
Product Code:
RPES0477
Size:
10µg
Species:
Mouse
Expressed Host:
Human Cells
Synonyms:
CD120b,p75,TNF-alphaR2,TNF-R-II,TNF-R2,TNF-R75,TNFalpha-R2,TNFBR,Tnfr-1,Tnfr2,TNFR80,TNFRII,Tumor necrosis factor receptor superfamily member 1b,Tnfrsf1b
Accession:
NP_035740.2
Sequence:
Val23-Gly258
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Mouse Tumor Necrosis Factor Receptor II is produced by our Mammalian expression system and the target gene encoding Val23-Gly258 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by SDS-PAGE
Mol Mass:
26.4 kDa
AP Mol Mass:
42 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
