Chitinase 3-like 3 gene, also known as YM1 and ECF-L, encodes a precursor protein with 398 amino acid residues with a 21 residue signal sequence. Chitinase 3-like 3 protein is a lectin that binds saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much stronger than binding to mono- or disaccharides. Also binds heparin and G1cN oligomers, and is produced primarily by macrophages during inflammation. It has chemotactic activity for T-lymphocytes, bone marrow cells and eosinophils.
Product Name:
Mouse YM1/ECF-L/Chil3 Recombinant Protein (RPES1950)
Product Code:
RPES1950
Size:
10µg
Species:
Mouse
Expressed Host:
Human Cells
Synonyms:
CHI3L3, Chitinase-like protein 3, Chil3,Ym1
Accession:
O35744
Sequence:
Tyr22-Tyr398(Pro105Ser)
Fusion tag:
C-His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Mouse CHI3L3 is produced by our Mammalian expression system and the target gene encoding Tyr22-Tyr398(Pro105Ser) is expressed with a 6His tag at the C-terminus.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
43.4 kDa
AP Mol Mass:
42-50 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
