Clec4b2, also known as mDCAR1, is a member of the DCIR/DCAR family. Expression of Clec4b2 was strongly tissue dependent. Clec4b2 expression on DCs was restricted to the CD8(+) DC subset in spleen and thymus and on subpopulations of CD11b(+) myeloid cells in bone marrow and spleen, whereas the molecule was not detectable on both cell types in lymph nodes and peripheral blood. Clec4b2 is a functional receptor on cells of the immune system and provides further insights into the regulation of immune responses by CLRs.
Product Name:
Rat CLEC4B2/mDCAR1 Recombinant Protein (RPES5021)
Product Code:
RPES5021
Size:
100 µg
Species:
Rat
Expressed Host:
HEK293 Cells
Synonyms:
CLEC4B2,Aplra1
Accession:
Q67DU9
Sequence:
Met44-Leu208
Fusion tag:
N-His
Endotoxin:
<1.0 EU per µg of the protein as determined by the LAL method
Protein Construction:
A DNA sequence encoding the rat CLEC4B2 (Q67DU9) (Met44-Leu208) was expressed with a polyhistidine tag at the N-terminus.
Purity:
> 85 % as determined by SDS-PAGE
Mol Mass:
21.8 kDa
AP Mol Mass:
31-36 kDa
Formulation:
Lyophilized from sterile PBS, pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
