Recombinant Rat IL-4 Protein (RPCB2008)
- SKU:
- RPCB2008
- Size:
- 10µg
- Tag:
- C-His
- Reactivity:
- Rat
- Expression Host:
- HEK293 cells
Description
| Product Name: | Recombinant Rat IL-4 Protein |
| SKU: | RPCB2008 |
| Size: | 10µg |
| Tag: | C-His |
| Reactivity: | Rat |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Rat IL-4 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | <0.01EU/μg of the protein by LAL method. |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
| Gene ID: | 287287 |
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | P20096 |
 | Recombinant Rat IL-4 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 15-25 kDa. |
 | Recombinant Rat IL-4 stimulates cell proliferation assay using TF-1 Human erythroleukemic cells. The ED₅₀ for this effect is 0.65-2.6 μg/mL, corresponding to a specific activity of 3.85×102~1.54×103 units/mg. |
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