The RFX2 Polyclonal Antibody (CAB17525) is a valuable tool for researchers studying the RFX2 protein, a transcription factor involved in the regulation of genes related to immune responses and development. This antibody, derived from rabbits, exhibits high specificity and sensitivity for detecting RFX2 in human samples, making it an ideal choice for Western blot applications.RFX2, also known as Regulatory Factor X 2, plays a crucial role in the control of gene expression in immune cells and is implicated in various cellular processes, including differentiation and proliferation.
Its involvement in immune regulation makes it a compelling target for investigation in studies focusing on immunology and cancer research.By utilizing the RFX2 Polyclonal Antibody, researchers can effectively study the function and expression of RFX2 in different cell types, providing valuable insights into its role in immune responses and potential implications for therapeutic interventions. This antibody serves as a reliable tool for advancing our understanding of the complex mechanisms underlying immune regulation and disease pathogenesis.
Product Name:
RFX2 Rabbit Polyclonal Antibody
SKU:
CAB17525
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 295-450 of human RFX2 (NP_000626.2).
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites.
Purification Method:
Affinity purification
Gene ID:
5990
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from DU145 cells, using RFX2 Rabbit pAb (CAB17525) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
