The RND2 Polyclonal Antibody (PAC01186) is a valuable tool for research involving RND2, a protein involved in cell signaling and migration. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications. It targets the RND2 protein, allowing for detection and analysis in a variety of cell types, making it ideal for studies in cell biology and cancer research.RND2, also known as Rho family GTPase 2, plays a crucial role in regulating cytoskeletal dynamics and cell movement.
Its involvement in cell migration and invasion makes it a potential target for research into cancer metastasis and other diseases characterized by abnormal cell motility. Studying the function of RND2 can provide insights into the mechanisms underlying these processes and may lead to the development of novel therapeutic strategies targeting this pathway.
RND2: May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily. Belongs to the small GTPase superfamily. Rho family.Protein type: G protein; G protein, monomeric; G protein, monomeric, RhoChromosomal Location of Human Ortholog: 17q21.31Molecular Function: GTPase activity; protein bindingBiological Process: signal transduction
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1. [provided by RefSeq, Jul 2008]
