The RNF168 Antibody (CAB3556) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the RNF168 protein, enabling precise detection and analysis in various cell types, making it an ideal choice for studies in genetics, oncology, and DNA repair pathways.RNF168, a Ring finger protein, plays a crucial role in the DNA damage response by facilitating the recruitment of repair factors to sites of DNA damage, maintaining genome stability and preventing the accumulation of mutations.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
RNF168 Antibody
SKU:
CAB3556
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
RIDL, hRNF168, RNF168
Positive Sample:
HeLa, Jurkat, MCF7, Mouse brain
Cellular Localization:
Nucleus.
Calculated MW:
65kDa
Observed MW:
65kDa
This gene encodes an E3 ubiquitin ligase protein that contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. The protein is involved in DNA double-strand break (DSB) repair. Mutations in this gene result in Riddle syndrome.
Purification Method
Affinity purification
Gene ID
165918
RRID
AB_2765157
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using RNF168 Rabbit pAb (CAB3556) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
