The RNF214 Antibody (PAC017005) is a valuable tool for researchers studying the RNF214 protein, a key player in various cellular processes. This polyclonal antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the RNF214 protein, this antibody enables accurate detection and analysis in a wide range of cell types, making it an ideal choice for studies in molecular biology and cancer research.
RNF214, also known as Ring Finger Protein 214, is involved in important cellular functions such as protein degradation and regulation of gene expression. Its role in these processes makes it a promising target for research into diseases such as cancer, neurodegenerative disorders, and metabolic conditions. By understanding the function of RNF214, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially develop targeted therapies to treat them.
Antibody Name:
RNF214 Antibody (PACO17005)
Antibody SKU:
PACO17005
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:5000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human RNF214
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Hepg2 cells, Primary antibody: PACO17005(RNF214 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds.
Background:
RNF214 (RING finger protein 214) is a 703 amino acid, protein that contains one RING-type zinc finger and is encoded by a gene that maps to human chromosome 11q23.3. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Synonyms:
ring finger protein 214
UniProt Protein Function:
RNF214: 2 isoforms of the human protein are produced by alternative splicingProtein type: Ubiquitin conjugating systemChromosomal Location of Human Ortholog: 11q23.3Molecular Function: zinc ion binding
