The RPL3L Polyclonal Antibody (PAC023370) is a valuable tool for researchers studying RPL3L, a ribosomal protein involved in protein synthesis and cell growth. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the RPL3L protein, it allows for the detection and analysis of RPL3L in various cell types, making it ideal for studies in molecular biology and cancer research.RPL3L is known to play a crucial role in ribosomal function and protein synthesis, making it a key target for investigation in cancer biology and other diseases characterized by abnormal cell growth.
Understanding the function of RPL3L is essential for identifying potential therapeutic targets and developing strategies to manipulate protein synthesis in cancer cells. With its high reactivity and specificity, the RPL3L Polyclonal Antibody is a valuable tool for researchers looking to explore the role of RPL3L in cellular processes and disease pathways.
Synthesized peptide derived from internal of human RPL3L.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemistry analysis of paraffin-embedded human heart tissue using RPL3L antibody.
Immunofluorescence analysis of MCF-7 cells, using RPL3L antibody.
Background:
This gene encodes a protein that shares sequence similarity with ribosomal protein L3. The protein belongs to the L3P family of ribosomal proteins. Unlike the ubiquitous expression of ribosomal protein genes, this gene has a tissue-specific pattern of expression, with the highest levels of expression in skeletal muscle and heart. It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome.
Synonyms:
60S ribosomal protein L3-like;
UniProt Protein Function:
RPL3L: a protein that shares sequence similarity with ribosomal protein L3. The protein belongs to the L3P family of ribosomal proteins. Unlike the ubiquitous expression of ribosomal protein genes, this gene has a tissue-specific pattern of expression, with the highest levels of expression in skeletal muscle and heart. It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome. [provided by RefSeq, Jul 2008]Protein type: Ribosomal; TranslationChromosomal Location of Human Ortholog: 16p13.3Cellular Component: membrane; ribosome; cytosolMolecular Function: structural constituent of ribosome; RNA bindingBiological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translational elongation; translation; viral reproduction; mRNA catabolic process, nonsense-mediated decay; translational initiation; viral transcription; gene expression; viral infectious cycle; translational termination
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that shares sequence similarity with ribosomal protein L3. The protein belongs to the L3P family of ribosomal proteins. Unlike the ubiquitous expression of ribosomal protein genes, this gene has a tissue-specific pattern of expression, with the highest levels of expression in skeletal muscle and heart. It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome. [provided by RefSeq, Jul 2008]
