Description
RPS15 Antibody (PACO04967)
The RPS15 Polyclonal Antibody (PAC004967) is a vital tool for researchers studying the RPS15 protein, a key component of the ribosomal subunit. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the RPS15 protein, this antibody allows for precise detection and analysis in multiple cell types, making it ideal for investigations in molecular biology and cancer research.
RPS15 is a critical player in protein synthesis, specifically in the formation of the ribosome, essential for cellular function. Dysregulation of RPS15 has been linked to various diseases, including cancer and genetic disorders, highlighting its importance in cellular processes. By delving into the function of RPS15, researchers can gain valuable insights into disease mechanisms and potentially identify novel therapeutic targets in these conditions.
| Antibody Name: | RPS15 Antibody |
| Antibody SKU: | PACO04967 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the Internal region of human Ribosomal Protein S15. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | RPS15; RIG; 40S ribosomal protein S15; RIG protein |
| UniProt Protein Function: | RPS15: a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19P family of ribosomal proteins. It is located in the cytoplasm. This gene has been found to be activated in various tumors, such as insulinomas, esophageal cancers, and colon cancers. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Ribosomal; RNA-binding Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: cytoplasm; cytosol; focal adhesion; membrane; nucleoplasm Molecular Function:protein binding; structural constituent of ribosome Biological Process: mRNA catabolic process, nonsense-mediated decay; osteoblast differentiation; ribosomal small subunit assembly and maintenance; ribosomal small subunit biogenesis and assembly; ribosomal small subunit export from nucleus; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription |
| NCBI Summary: | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19P family of ribosomal proteins. It is located in the cytoplasm. This gene has been found to be activated in various tumors, such as insulinomas, esophageal cancers, and colon cancers. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] |
| UniProt Code: | P62841 |
| NCBI GenInfo Identifier: | 51338641 |
| NCBI Gene ID: | 6209 |
| NCBI Accession: | P62841.2 |
| UniProt Secondary Accession: | P62841,P11174, Q3KRA1, Q9UDC2, A5D8V9, |
| UniProt Related Accession: | P62841 |
| Molecular Weight: | 17,040 Da |
| NCBI Full Name: | 40S ribosomal protein S15 |
| NCBI Synonym Full Names: | ribosomal protein S15 |
| NCBI Official Symbol: | RPS15Â Â |
| NCBI Official Synonym Symbols: | RIG; S15Â Â |
| NCBI Protein Information: | 40S ribosomal protein S15 |
| UniProt Protein Name: | 40S ribosomal protein S15 |
| UniProt Synonym Protein Names: | RIG protein |
| Protein Family: | 30S ribosomal protein |
| UniProt Gene Name: | RPS15Â Â |
| UniProt Entry Name: | RS15_HUMAN |
