The RPS29 Polyclonal Antibody (PAC057952) is a valuable tool for studying RPS29, a ribosomal protein involved in protein synthesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the RPS29 protein, researchers can detect and analyze its expression in various cell types, making it ideal for investigations in molecular biology and cancer research.RPS29 is a crucial component of the ribosome, the cellular machinery responsible for translating genetic information into proteins. Its role in protein synthesis makes it a key target for understanding cellular processes related to growth, development, and disease.
Research on RPS29 is essential for uncovering insights into conditions like cancer, where abnormalities in protein production can drive uncontrolled cell growth.Overall, the RPS29 Polyclonal Antibody offers researchers a reliable tool for studying the function and regulation of RPS29 in various biological contexts. Its use in Western blot analyses can provide valuable information for advancing our understanding of protein synthesis and its implications in health and disease.
Antibody Name:
RPS29 Antibody (PACO57952)
Antibody SKU:
PACO57952
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human 40S ribosomal protein S29 protein (2-56AA)
Immunofluorescent analysis of HepG2 cells using PACO57952 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
cytoplasm, cytosol, cytosolic small ribosomal subunit, extracellular exosome, focal adhesion, nucleoplasm, small ribosomal subunit, structural constituent of ribosome, zinc ion binding, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Synonyms:
40S ribosomal protein S29 (Small ribosomal subunit protein uS14), RPS29
UniProt Protein Function:
RPS29: a ribosomal protein that is a component of the 40S subunit and a member of the S14P family of ribosomal proteins. The protein, which contains a C2-C2 zinc finger-like domain that can bind to zinc, can enhance the tumor suppressor activity of Ras-related protein 1A (KREV1). It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]Protein type: Translation; RibosomalChromosomal Location of Human Ortholog: 14qCellular Component: small ribosomal subunit; focal adhesion; cytoplasm; cytosolMolecular Function: structural constituent of ribosome; zinc ion bindingBiological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translational elongation; viral reproduction; translation; mRNA catabolic process, nonsense-mediated decay; translational initiation; viral transcription; gene expression; translational termination; viral infectious cycleDisease: Diamond-blackfan Anemia 13
UniProt Protein Details:
NCBI Summary:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit and a member of the S14P family of ribosomal proteins. The protein, which contains a C2-C2 zinc finger-like domain that can bind to zinc, can enhance the tumor suppressor activity of Ras-related protein 1A (KREV1). It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]
