The SCMH1 Polyclonal Antibody (PACO12052) is a valuable tool for researchers studying SCMH1, a protein involved in chromatin structure regulation. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot and immunohistochemistry applications. By binding specifically to SCMH1, this antibody enables accurate detection and analysis of the protein in various cell types, making it ideal for investigations in epigenetics and cancer research.
SCMH1, also known as subunit of the polycomb repressive complex 1, plays a crucial role in chromatin organization and gene expression regulation. Its involvement in epigenetic processes makes it a promising target for studies on developmental disorders, cancer progression, and other diseases influenced by chromatin modifications. Understanding the function of SCMH1 is essential for developing targeted therapies that modulate gene expression for therapeutic purposes.
sex comb on midleg homolog 1 (Drosophila);SCMH1;Scml3 ;
UniProt Protein Function:
SCMH1: Associates with Polycomb group (PcG) multiprotein complexes; the complex class is required to maintain the transcriptionally repressive state of some genes. Belongs to the SCM family. 6 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 1p34Cellular Component: nucleoplasm; nucleus; chromocenterMolecular Function: DNA binding; transcription factor activityBiological Process: anterior/posterior pattern formation; chromatin remodeling; anatomical structure morphogenesis; transcription, DNA-dependent; spermatogenesis; gene silencing; negative regulation of transcription, DNA-dependent
