The SCN2B Antibody (CAB7723) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in a variety of applications including Western blot, immunofluorescence, and immunohistochemistry.SCN2B is known to be involved in regulating the function of sodium channels in the nervous system, impacting neuronal signaling and neurotransmission. Dysregulation of SCN2B has been implicated in various neurological disorders such as epilepsy, autism, and schizophrenia, making it an important target for research in neurobiology and neurology.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
SCN2B Antibody
SKU:
CAB7723
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ATFB14, SCN2B
Positive Sample:
SW620, HepG2
Cellular Localization:
Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
24kDa
Observed MW:
24kDa
The protein encoded by this gene is the beta 2 subunit of the type II voltage-gated sodium channel. The encoded protein is involved in cell-cell adhesion and cell migration. Defects in this gene can be a cause of Brugada Syndrome, atrial fibrillation, or sudden infant death syndrome.
Purification Method
Affinity purification
Gene ID
6327
RRID
AB_2772162
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using SCN2B Rabbit pAb (CAB7723) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
