The SEC24C Polyclonal Antibody (CAB10797) is a valuable tool for researchers studying SEC24C, a key protein involved in protein trafficking and secretion within cells. This antibody, produced through rabbit immunization, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SEC24C protein, this antibody enables precise detection and analysis in various cell types, making it a versatile option for studies in cell biology, molecular biology, and protein trafficking research.
SEC24C is a component of the COPII complex, which is responsible for packaging proteins into vesicles for transport from the endoplasmic reticulum to the Golgi apparatus. Dysregulation of SEC24C activity has been implicated in various diseases, including neurological disorders, metabolic conditions, and cancer. Investigating the function of SEC24C with the help of this polyclonal antibody can provide valuable insights into cellular processes and disease mechanisms, potentially leading to the development of targeted therapies and diagnostic tools.
Product Name:
SEC24C Rabbit Polyclonal Antibody
SKU:
CAB10797
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 915-1094 of human SEC24C (NP_004913.2).
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified.
Purification Method:
Affinity purification
Gene ID:
9632
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SEC24C Rabbit pAb (CAB10797) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
