The SEMG1 Polyclonal Antibody (CAB24532) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in various applications, including Western blotting. By specifically binding to the SEMG1 protein, this antibody enables precise detection and analysis in a range of cell types, making it a key resource for investigations in reproductive biology and fertility research.SEMG1, also known as semenogelin-1, plays a critical role in sperm motility and fertility by contributing to the formation of the sperm plasma membrane. Dysregulation of SEMG1 has been associated with male infertility, making it a target of interest for studies on reproductive health and assisted reproductive technologies.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
SEMG1 Polyclonal Antibody
SKU:
CAB24532
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. This preproprotein is proteolytically processed by the prostate-specific antigen (PSA) protease to generate multiple peptide products that exhibit distinct functions. One of these peptides, SgI-29, is an antimicrobial peptide with antibacterial activity. This proteolysis process also breaks down the gel matrix and allows the spermatozoa to move more freely. This gene and another similar semenogelin gene are present in a gene cluster on chromosome 20.
Purification Method
Affinity purification
Gene ID
6406
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from wild type (WT) and 293T cells transfected with SEMG1, using SEMG1 Rabbit pAb (CAB24532) at 1:400 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3s.
