The SERINC2 Polyclonal Antibody (PAC020437) is a valuable tool for researchers studying SERINC2, a protein involved in various cellular processes, including viral infectivity and immune response modulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the SERINC2 protein, this antibody enables the detection and analysis of SERINC2 expression in different cell types, making it essential for studies in virology, immunology, and related fields.
SERINC2 is a transmembrane protein that has been implicated in the restriction of retroviral infections by promoting the incorporation of host cell membrane lipids into viral particles. Additionally, SERINC2 has been shown to play a role in modulating immune responses, making it a potential target for therapeutic interventions in viral infections and immune-related disorders. Research on SERINC2 is crucial for understanding its functions and developing strategies to manipulate its activity for medical applications.
Antibody Name:
SERINC2 Antibody (PACO20437)
Antibody SKU:
PACO20437
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human SERINC2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20437(SERINC2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20437(SERINC2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
SERINC2 involved in phosphatidylserine metabolic process, and positive regulation of transferase activity.
Synonyms:
serine incorporator 2
UniProt Protein Function:
SERINC2: Belongs to the TDE1 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 1p35.1Cellular Component: integral to membraneMolecular Function: L-serine transmembrane transporter activity
