The Serinc3 Antibody (PAC020439) is a valuable tool for researchers studying Serinc3, a protein associated with lipid metabolism and viral infection. This polyclonal antibody, produced in rabbits, has been validated for use in various applications, including Western blot and Immunohistochemistry. It specifically targets the Serinc3 protein, enabling precise detection and analysis in different cell types and tissues.Serinc3 is known for its role in regulating lipid homeostasis and its potential involvement in viral entry and replication. Its functions make it a promising target for studies related to metabolic disorders, infectious diseases, and antiviral drug development.
By using the Serinc3 Antibody, researchers can gain insights into the mechanisms underlying these processes and potentially discover new therapeutic strategies.Overall, the Serinc3 Antibody is a reliable tool for researchers seeking to explore the functions and implications of Serinc3 in various biological contexts. Its high specificity and reactivity with human samples make it a valuable asset for studies in molecular biology, virology, and metabolism research.
Antibody Name:
SERINC3 Antibody (PACO20439)
Antibody SKU:
PACO20439
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:1000-1:2000, WB:1:200-1:1000
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human SERINC3
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 8%SDS-PAGE,Lysate: 40 µg,Lane 1-2: Human right lung cancer tissue, Human left lung cancer tissue,Primary antibody: PACO20439(SERINC3 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 3 minutes.
Background:
TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue.
Synonyms:
serine incorporator 3
UniProt Protein Function:
SERINC3: May be involved in cellular transformation. Belongs to the TDE1 family.
UniProt Protein Details:
Protein type:Cell surface; Membrane protein, multi-pass; Membrane protein, integral
