The SERINC4 Polyclonal Antibody (PAC020441) is a valuable tool for researchers studying SERINC4, a protein involved in regulating viral entry and immune response. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the SERINC4 protein, this antibody enables detection and analysis in a variety of cell types, making it ideal for research in virology and immunology.SERINC4 is known for its role in inhibiting viral infection by modulating the entry of viruses into host cells.
Understanding the mechanisms by which SERINC4 functions can provide insights into developing antiviral strategies and therapies. Research on SERINC4 is particularly relevant in the context of viral infections and understanding the host immune response to pathogens.By utilizing the SERINC4 Polyclonal Antibody (PAC020441), researchers can uncover the molecular mechanisms underlying viral entry and immune regulation, ultimately contributing to the development of novel antiviral therapies and strategies to combat viral infections.
Antibody Name:
SERINC4 Antibody (PACO20441)
Antibody SKU:
PACO20441
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:5000, WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human SERINC4
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 8%SDS-PAGE,Lysate: 40 μgPrimary antibody: PACO20441(SERINC4 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 5 minutes.
Background:
SERINC4 (serine incorporator 4) is a 518 amino acid, multi-pass membrane protein that belongs to the TDE1 family. The SERINC4 protein Incorporates a polar amino acid, serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids. Because SERINC proteins contain 11 transmembrane segments resembling amino acid, transporters, SERINC4 may also function as an L-serine transporter by carrying serine molecules into the hydrophobic milieu of membrane lipid bilayers.
Synonyms:
serine incorporator 4
UniProt Protein Function:
SERINC4: Incorporates a polar amino acid serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids. Belongs to the TDE1 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 15q15.3Cellular Component: integral to membraneMolecular Function: L-serine transmembrane transporter activity
