The Serinc4 Antibody (PAC020442) is a highly specific tool for researchers studying Serinc4, a protein involved in lipid metabolism and immune response regulation. This antibody, generated in rabbits, has been extensively validated for use in various applications, including Western blotting and immunofluorescence.Serinc4 is known to play a role in the regulation of lipid biosynthesis and immune signaling pathways, making it a key target for investigation in the fields of metabolism, immunology, and cancer research.
By targeting Serinc4 with this antibody, researchers can gain valuable insights into its function and potential therapeutic implications in various disease contexts.Overall, the Serinc4 Antibody (PAC020442) is an essential tool for researchers looking to further explore the role of Serinc4 in cellular processes and disease pathogenesis, ultimately advancing our understanding of lipid metabolism and immune regulation.
Antibody Name:
SERINC4 Antibody (PACO20442)
Antibody SKU:
PACO20442
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:1000-1:2000, WB:1:200-1:1000
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human SERINC4
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 8%SDS-PAGE,Lysate: 40 μgPrimary antibody: PACO20442(SERINC4 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute.
Background:
SERINC4 (serine incorporator 4) is a 518 amino acid, multi-pass membrane protein that belongs to the TDE1 family. The SERINC4 protein Incorporates a polar amino acid, serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids. Because SERINC proteins contain 11 transmembrane segments resembling amino acid, transporters, SERINC4 may also function as an L-serine transporter by carrying serine molecules into the hydrophobic milieu of membrane lipid bilayers.
Synonyms:
serine incorporator 4
UniProt Protein Function:
SERINC4: Incorporates a polar amino acid serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids. Belongs to the TDE1 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 15q15.3Cellular Component: integral to membraneMolecular Function: L-serine transmembrane transporter activity
