The SH3BP5 Polyclonal Antibody (PAC012183) is a valuable tool for researchers studying the SH3BP5 protein, also known as SH3 domain-binding protein 5, which plays a critical role in various cellular processes. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.SH3BP5 is involved in signaling pathways related to cell growth, survival, and migration, making it a key player in cancer development and progression. By specifically binding to the SH3BP5 protein, this antibody enables researchers to detect and analyze its expression in different cell types, facilitating studies in cancer biology and therapeutic development.
Understanding the function of SH3BP5 is essential for uncovering its potential as a therapeutic target for cancer treatment. By elucidating its role in oncogenic signaling pathways, researchers can identify novel strategies to inhibit cancer cell growth and metastasis. The SH3BP5 Polyclonal Antibody offers a reliable tool for investigating the role of SH3BP5 in cancer biology and advancing the development of targeted cancer therapies.
SH3-domain binding protein 5 (BTK-associated);SH3BP5;SAB ;
UniProt Protein Function:
SH3BP5: Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death. Belongs to the SH3BP5 family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 3p24.3Cellular Component: mitochondrion; cytoplasmMolecular Function: protein binding; protein kinase inhibitor activity; SH3 domain bindingBiological Process: negative regulation of protein kinase activity; signal transduction
