The SIGLEC6 Antibody (CAB12387) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is raised in rabbits and is highly specific for detecting Siglec6 in human samples. Validated for use in Western blot applications, this antibody binds to the Siglec6 protein, allowing for accurate detection and analysis in a variety of cell types.Siglec6 has been implicated in various immune processes, including regulation of immune responses and interactions with sialic acid-containing molecules. Research into Siglec6 has highlighted its potential role in modulating immune function in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
SIGLEC6 Antibody
SKU:
CAB12387
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Cell Membrane, Secreted, Single-Pass Type I Membrane Protein.
Calculated MW:
50kDa
Observed MW:
72kDa
This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins. The encoded transmembrane receptor binds sialyl-TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia.
Purification Method
Affinity purification
Gene ID
946
RRID
AB_2759231
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from U-937 cells, using SIGLEC6 Rabbit pAb (CAB12387) at 1:700 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
