The SIN3A Antibody (CAB13928) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has high specificity for human samples and is validated for use in Western blot applications. By binding to the SIN3A protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and epigenetics.SIN3A plays a key role in gene expression regulation by recruiting chromatin-modifying enzymes to specific genomic loci, impacting various cellular processes such as proliferation, differentiation, and apoptosis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
SIN3A Antibody
SKU:
CAB13928
Size:
20μL, 100μL
Reactivity:
Human, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
WITKOS, DEL15Q24, CHR15DELq24, Sin3A
Positive Sample:
293T
Cellular Localization:
Nucleus, Nucleolus.
Calculated MW:
145kDa
Observed MW:
147kDa
The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex.
Purification Method
Affinity purification
Gene ID
25942
RRID
AB_2760780
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from 293T cells, using Sin3A Rabbit pAb (CAB13928) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.