The SLC16A10 Polyclonal Antibody (PAC020477) is a valuable tool for researchers studying SLC16A10, a member of the solute carrier family involved in transporting monocarboxylates such as lactate and pyruvate across cell membranes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples and is suitable for use in Western blot applications. By binding to the SLC16A10 protein, this antibody enables the detection and analysis of SLC16A10 expression in a variety of cell types, making it an ideal choice for studies related to metabolism, cancer, and other physiological processes.SLC16A10, also known as MCT10, plays a crucial role in regulating the intracellular levels of monocarboxylates, which are essential for energy metabolism and cellular function.
Dysregulation of SLC16A10 has been implicated in various diseases, including metabolic disorders and cancer. Therefore, investigating the function and expression of SLC16A10 using this polyclonal antibody can provide valuable insights into the role of this transporter in health and disease. Researchers interested in understanding the mechanisms underlying metabolic dysregulation and developing potential therapeutic interventions will find this antibody to be a valuable asset in their studies.
Antibody Name:
SLC16A10 Antibody (PACO20477)
Antibody SKU:
PACO20477
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:1000-1:2000, WB:1:200-1:1000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide of human SLC16A10
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane: Mouse pancreas tissue, Primary antibody: PACO20477(SLC16A10 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes.
Background:
SLC16A10 is a member of a family of plasma membrane amino acid, transporters that mediate the Na(+)-independent transport of aromatic amino acid, across the plasma membrane. Sodium-independent transporter that mediates the update of aromatic acid, Can function as a net efflux pathway for aromatic amino acid, in the basosolateral epithelial cells.
Synonyms:
solute carrier family 16 (aromatic amino acid, transporter), member 10
UniProt Protein Function:
SLC16A10: Sodium-independent transporter that mediates the update of aromatic acid. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
UniProt Protein Details:
Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Biological Process: amino acid transport; aromatic amino acid transport
NCBI Summary:
SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent transport of aromatic amino acids across the plasma membrane.[supplied by OMIM, Apr 2004]
