The SLC16A10 Polyclonal Antibody (PACO20478) is a valuable tool for researchers studying SLC16A10, a member of the solute carrier family involved in transporting small solutes across cell membranes. This antibody, generated in rabbits, exhibits high specificity and sensitivity toward human samples, making it suitable for use in Western blot applications. By binding to the SLC16A10 protein, this antibody facilitates its detection and analysis in various cell types, making it an ideal choice for studies in metabolism and transport processes.SLC16A10 is known for its role in transporting monocarboxylates, such as lactate and pyruvate, across cell membranes, contributing to energy metabolism and metabolic homeostasis.
Its involvement in these crucial cellular processes highlights its potential significance in various metabolic disorders, including diabetes, obesity, and metabolic syndrome. Studying the function of SLC16A10 can provide valuable insights into the mechanisms underlying these conditions and aid in the development of targeted therapies.Overall, the SLC16A10 Polyclonal Antibody (PACO20478) is a reliable tool for researchers investigating the role of SLC16A10 in cellular metabolism and transport pathways. Its specificity, sensitivity, and suitability for Western blot applications make it a valuable asset for studies aiming to elucidate the function of SLC16A10 and its implications in metabolic disorders.
Antibody Name:
SLC16A10 Antibody (PACO20478)
Antibody SKU:
PACO20478
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human, Rat
Immunogen:
Synthetic peptide of human SLC16A10
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20478(SLC16A10 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO20478(SLC16A10 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
SLC16A10 is a member of a family of plasma membrane amino acid, transporters that mediate the Na(+)-independent transport of aromatic amino acid, across the plasma membrane. Sodium-independent transporter that mediates the update of aromatic acid, Can function as a net efflux pathway for aromatic amino acid, in the basosolateral epithelial cells.
Synonyms:
solute carrier family 16 (aromatic amino acid, transporter), member 10
UniProt Protein Function:
SLC16A10: Sodium-independent transporter that mediates the update of aromatic acid. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
UniProt Protein Details:
Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Biological Process: amino acid transport; aromatic amino acid transport
NCBI Summary:
SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent transport of aromatic amino acids across the plasma membrane.[supplied by OMIM, Apr 2004]
