The SLC16A11 Polyclonal Antibody (PACO20479) is specifically designed for research involving SLC16A11, a member of the SLC16A family of transporters that play a key role in metabolic regulation. The antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in various applications, including Western blot analysis. By binding to the SLC16A11 protein, this antibody allows for accurate detection and analysis in different cell types, making it an ideal tool for studies in metabolism and related research areas.
SLC16A11 is a transporter protein known to be involved in the regulation of glucose and lipid metabolism, making it a potential target for therapeutic interventions in metabolic disorders such as diabetes and obesity. Understanding the function and regulation of SLC16A11 is crucial for developing strategies to modulate its activity and potentially treat metabolic diseases effectively. This antibody offers researchers the means to investigate the role of SLC16A11 in metabolic pathways and explore its potential as a therapeutic target in metabolic disorders.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20479(SLC16A11 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
Gel: 8%SDS-PAGE,Lysate: 40 μgPrimary antibody: PACO20479(SLC16A11 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 2 minutes.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20479(SLC16A11 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
MCT11 (Monocarboxylate transporter 11), also known as SLC16A11 (Solute carrier family 16 member 11), is a 471 proton-linked monocarboxylate transporter that catalyzes the rapid transport of monocarboxylates across the plasma membrane.
Synonyms:
solute carrier family 16, member 11
UniProt Protein Function:
SLC16A11: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.Protein type: Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass; TransporterChromosomal Location of Human Ortholog: 17p13.1Cellular Component: endoplasmic reticulum membrane; integral to plasma membraneMolecular Function: lactate transmembrane transporter activityBiological Process: lipid metabolic process
